Johnny Quinlan heads a household that includes his wife Bertha, his sister, Lottie, and Bertha's brother, Dan Walsh, an unemployed, aspiring saxophone player. When Johnny loses his job as a drugstore clerk, he is afraid to tell the loving, but practical Bertha, and scours the city to find a new job. Bertha soon finds out, though, and despite having some savings, the family's bills begin to mount while Johnny remains unemployed. One day, Frederick "Nifty" Herman, an acquaintance of Johnny, who runs a florist's shop as a front for his drug dealing but whom Johnny believes is a bootlegger, loans Johnny fifteen dollars and offers him a job. Knowing that Bertha would not like him to work as a bootlegger, Johnny turns Nifty down. Despite weeks of unemployment, Johnny is insulted when he returns home one day and Bertha insists on asking their neighbor, Mrs. Bercowich, to ask her husband to give Johnny a job cleaning fish. When Nifty later tells Johnny that a man named Kilpapa, who owns a chain of drugstores, wants to hire Johnny to manage one of his stores, but first needs him to keep a suitcase of "high class" liquor safe for a short time, Johnny agrees. He then takes the suitcase home, but Bertha is suspicious, and he reluctantly admits that it belongs to Nifty. Fearful that association with Nifty and his friends will eventually turn Johnny into a criminal, too, Bertha threatens to leave him unless he takes the suitcase back. Johnny then attempts to return it but the flower shop is closed and he has no other choice than to bring it back to the apartment. Although Johnny hides the suitcase under a chair, Lottie accidentally discovers it while the family is having dinner with Charles Newton, Lottie's boss and sweetheart. Newton, who is a government agent, recognizes the suitcase as one that he and his men have been trailing in their pursuit of a narcotics gang. Johnny, who has always hated drug dealers, is furious when the suitcase is opened and he sees that, instead of “hooch,” it contains narcotics, but Newton has no other choice but to arrest him. However, before they leave the apartment, Nifty arrives, and Johnny devises a plan to have Newton and his detectives, Keefe and Burke, secretly listen as Johnny tricks Nifty into revealing that Johnny was unaware of the true contents of the suitcase. When Nifty also reveals that he himself is Kilpapa, Johnny knocks him down, after which Newton, Keefe and Burke arrest Nifty and take him away. Impressed with Johnny's quick action, Newton then offers him a job and proposes to Lottie, who happily accepts.